The museum was founded in 1859, its establishment was initiated by the Benedictine monk from Győr, Flóris Rómer. The collections continued to grow throughout history, today the institution boasts 11 places for exhibitions. Among the museums more significant exhibitions are the Radnai Collection in the Esterhazy Palace, the Győr Graphic Design Workshop and Exhibition Hall located in the Napoleon House, the Margit Kovács Permanent Exhibition in the Kreszta House, the Vasilescu Collection in the Synagogue, the several collections showcased in the Apátúr House, the History of the Masonry Heater Exhibition in the Fruhmann House, the temporary exhibitions held in the Rómer House, the exhibition of the Castle Catacombs Lapidarium. The museum has a nationwide circle of collectors, it features, among others, the works of 20th century and contemporary Hungarian and international artists alike.

The Lachmann family dealt mainly in the production and sale of small-series men's clothing. The trade sign, depicting a pair a scissors hangs above their oldest shop and indicates that the tailoring service still operates today as it has for over 100 years.

A family in Győr has been dealing in blue dyeing since 1906, their shop is located on the corner of Dr. Kovács Pál Street and Jedlik Ányos Street. The trade sign hanging above depicts a blue-dyeing girl and was made by Ferenc Lebó, a sculptor from Győr, in 2015.